It’s Tuesday, May 20, and the Tigers (31-17) are in St. Louis to take on the Cardinals (27-21). Tarik Skubal is slated to take the mound for Detroit against Erick Fedde for St. Louis.

The Cardinals won Game 1 of the series, 11-4, behind a 5-0 lead through five innings and 11-0 through seven. Only one run came off the homer for St. Louis yesterday, while all four of Detroit’s runs came in the eighth and ninth innings.

Let’s dive into the matchup and find a sweat or two. We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Tigers at Cardinals

  • Date: Tuesday, May 20, 2025
  • Time: 7:45 PM EST
  • Site: Busch Stadium
  • City: St. Louis, MO
  • Network/Streaming: FDSNDT, FDSNMW

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Tigers at the Cardinals

The latest odds as of Tuesday:

  • Moneyline: Tigers (-179), Cardinals (+149)
  • Spread: Tigers -1.5
  • Total: 7.0 runs

Probable starting pitchers for Tigers at Cardinals

  • Pitching matchup for May 20, 2025: Tarik Skubal vs. Erick Fedde
    • Tigers: Tarik Skubal, (4-2, 2.67 ERA)
      Last outing: 6.1 Innings Pitched, 5 Earned Runs Allowed, 7 Hits Allowed, 1 Walks, and 11 Strikeouts
    • Cardinals: Erick Fedde, (3-3, 3.44 ERA)
      Last outing: 5.2 Innings Pitched, 0 Earned Runs Allowed, 3 Hits Allowed, 4 Walks, and 3 Strikeouts

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Expert picks & predictions for tonight’s game between the Tigers and the Cardinals

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Tuesday’s game between the Tigers and the Cardinals:

  • Moneyline: NBC Sports Bet is recommending a play on the Detroit Tigers on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the St. Louis Cardinals at +1.5.
  • Total: NBC Sports Bet is recommending a play on the over on the Game Total of 7.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC.

Top betting trends & insights to know ahead of Tigers at Cardinals

  • After winning the series opener, the Tigers have a 7-4 record in game 2 this season
  • The Over is 12-9-1 in the Cardinals’ home games this season
  • The Cardinals have covered in 4 of their last 5 games for a profit of 1.96 units

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Brad Thomas (@MrBradThomas)



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