The club have been busy in the transfer market since winning promotion from the Championship.
Guiu is one of the players on their radar, as they look to add more power and pace in the final third.
The 19-year-old could arrive on a temporary deal from Chelsea, with no option to buy.
Journalist Fabrizio Romano claims Chelsea are open to letting Guiu leave on loan this summer. However, they want any club taking him to pay his full salary.
The Blues are not willing to include a buy option or a buy-back clause. The idea is for Guiu to gain first-team experience before returning to Stamford Bridge next summer.
The Spain youth international joined Chelsea from Barcelona and has already made an impact in the senior team. He played 16 matches under Enzo Maresca last season and scored six goals.
Sunderland manager Regis Le Bris wants to add a different profile of striker to his squad. He believes that Guiu could help their attack become more direct and effective.
He is a powerful centre-forward who thrives inside the penalty area. He is quick, strong and always looking to make runs behind the defence.
Although he does not offer much in terms of link-up play, he is dangerous in front of goal. His strength in the air and ability to press defenders add to his appeal.
Sunderland are hopeful of reaching an agreement with Chelsea in the coming days.
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