Its Monday, May 5 and the Guardians (20-14) are in Washington to take on the Nationals (16-19).
Luis L. Ortiz is slated to take the mound for Cleveland against Jake Irvin for Washington.
The Nationals took two of three over the weekend against Cincinnati. Yesterday Washington bested the Reds 4-1. The Nats scored three in the seventh to break a one-all tie and secure the win.
The Guardians took two of three against the Blue Jays and have now won five of their last six overall. Gabriel Arias collected three hits yesterday for Cleveland as the Guardians downed the Jays 5-4.
Lets dive into the matchup and find a sweat or two.
We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Guardians at Nationals
- Date: Monday, May 5, 2025
- Time: 6:45PM EST
- Site: Nationals Park
- City: Washington, DC
- Network/Streaming: CLEG, MASN
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Guardians at the Nationals
The latest odds as of Monday:
- Moneyline: Guardians (-118), Nationals (-102)
- Spread: Guardians -1.5
- Total: 9.0 runs
Probable starting pitchers for Guardians at Nationals
- Pitching matchup for May 5, 2025: Luis L. Ortiz vs. Jake Irvin
- Guardians: Luis L. Ortiz (2-3, 4.78 ERA)
Last outing: 4/30 vs. Minnesota – 6.1IP, 0ER, 3H, 2BB, 5Ks - Nationals: Jake Irvin (2-1, 4.01 ERA)
Last outing: 4/30 at Philadelphia – 6IP, 6ER, 8H, 3BB, 2Ks
- Guardians: Luis L. Ortiz (2-3, 4.78 ERA)
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Top betting trends & insights to know ahead of Guardians at Nationals
- The Guardians have won 8 of their last 10 road games against teams with losing records
- The Over is 10-6-2 in Guardians’ road games this season
- Dylan Crews has 1 hit in his last 21 ABs
- Jose Ramirez is 7-26 over his last 7 games
If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight’s game between the Guardians and the Nationals
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Monday’s game between the Guardians and the Nationals:
- Moneyline: NBC Sports Bet is recommending a play on the Cleveland Guardians on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the Washington Nationals at +1.5.
- Total: NBC Sports Bet is recommending a play on the over on the Game Total of 9.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
Follow our experts on socials to keep up with all the latest content from the staff:
- Jay Croucher (@croucherJD)
- Drew Dinsick (@whale_capper)
- Vaughn Dalzell (@VmoneySports)
- Brad Thomas (@MrBradThomas)
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