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The San Francisco Giants head east for a three-game weekend series with the Baltimore Orioles.
Friday’s series opener sees Landen Roupp get the nod for the visitors and Shane Baz take the bump for the home team.
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See why I’m backing the hosts in my Giants vs. Orioles predictions and MLB picks for April 10.
Who will win Giants vs Orioles today: Orioles (-125)
The Baltimore Orioles have an edge in starting pitching, the bullpen, and hitting, so I’m backing the home team as a slight favorite against the San Francisco Giants tonight.
San Francisco has been the worst team in the league against RHP (61 wRC+), and Baltimore has been slightly above average (104). The Orioles bullpen has posted a 3.94 FIP, compared to 4.47 for the Giants.
Baltimore right-hander Shane Baz’s velocity is up half a tick, and his 104 Stuff+ is encouraging, while San Francisco starter Landen Roupp has struggled with walks (3.97 per nine innings) and allowed seven runs to the Mets in his previous start.
Covers
COVERS INTEL:
These Giants hitters have 17 career at-bats against Baz, during which they’ve managed just two hits while striking out seven times.
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Giants vs Orioles Over/Under pick: Under 8.5 (-110)
These are two quality starting pitchers, as Roupp owns a 1.37 FIP, while Baz isn’t far behind at 2.88.
San Francisco has been miserable at the plate and now has to travel across the country and face a tough opponent. It doesn’t project as a breakout spot.
Baltimore has been on a prolonged Under stretch, going 13-22 O/U in its last 35 games dating back to last season.
JD Yonke’s 2026 Transparency Record
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ML/RL bets: 3-3, +0.25 units
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Over/Under bets: 3-4, -1.16 units
Giants vs Orioles odds
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Moneyline: Giants +105 | Orioles -125
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Run line: Giants +1.5 (-200) | Orioles -1.5 (+165)
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Over/Under: Over 8.5 (-110) | Under 8.5 (-110)
Giants vs Orioles trend
The Giants have lost 18 of their last 30 games. Find more MLB betting trends for Giants vs. Orioles.
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How to watch Giants vs Orioles and game info
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Location |
Oriole Park at Camden Yards, Baltimore, MD |
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Date |
Friday, April 10, 2026 |
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First pitch |
7:15 p.m. ET |
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TV |
Apple TV |
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Giants starting pitcher |
Landen Roupp |
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Orioles starting pitcher |
Shane Baz |
Giants vs Orioles latest injuries
Giants vs Orioles weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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