Its Friday, August 22 and the Astros (70-58) are in Baltimore to take on the Orioles (59-68).
Lance McCullers is slated to take the mound for Houston against Cade Povich for Baltimore.
The Astros jumped on the Orioles early last night scoring seven runs in the first three innings and rolled to a 7-2 win. Carlos Correa’s renaissance continues since returning to Houston. The veteran collected a couple hits and drove in two more last night. Correa is now hitting .338 for the Astros with two home runs and ten runs batted in. Jason Alexander won his fourth game of the season allowing just two runs over 5.1 innings. He has been a revelation since being promoted to the rotation with Houston winning his last five and seven of his last eight starts. The career minor leaguer’s story is all the more impressive when you consider that prior to this season Alexander had not pitched in the bigs since 2022.
Lets dive into the matchup and find a sweat or two.
We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch the first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Astros at Orioles
- Date: Friday, August 22, 2025
- Time: 11:05PM EST
- Site: Oriole Park at Camden Yards
- City: Baltimore, MD
- Network/Streaming: SCHN, MASN
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Astros at the Orioles
The latest odds as of Friday:
- Moneyline: Astros (-106), Orioles (-113)
- Spread: Orioles 1.5
- Total: 9.0 runs
Probable starting pitchers for Astros at Orioles
- Pitching matchup for August 22, 2025: Lance McCullers vs. Cade Povich
- Astros: Lance McCullers (2-4, 6.90 ERA)
Last outing: July 19 at Seattle – 13.50 ERA, 4 Earned Runs Allowed, 5 Hits Allowed, 3 Walks, and 1 Strikeouts - Orioles: Cade Povich (2-6, 4.98 ERA)
Last outing: August 16 at Houston – 5.40 ERA, 3 Earned Runs Allowed, 5 Hits Allowed, 3 Walks, and 10 Strikeouts
- Astros: Lance McCullers (2-4, 6.90 ERA)
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Top betting trends & insights to know ahead of Astros at Orioles
- The Under is 4-1 in the Orioles’ last 5 home games
- The Orioles have covered in their last 3 games against the Astros
- The Orioles have won 4 of their last 5 games against AL West teams
- Lance McCullers Jr. is making his first start since being sidelined for the past month (finger)
- Jose Altuve is hitless in his last three games (0-12)
If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight’s game between the Astros and the Orioles
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Friday’s game between the Astros and the Orioles:
- Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the Houston Astros at +1.5.
- Total: NBC Sports Bet is recommending a play on the over on the Game Total of 9.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC Sports.
Follow our experts on socials to keep up with all the latest content from the staff:
- Jay Croucher (@croucherJD)
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- Brad Thomas (@MrBradThomas)
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